Product image is illustrative. Your medication and packaging may look different.
No. 18 · Hair and skin
Spironolactone for Hormonal Acne
25 or 50 mg tablets
Spironolactone is a long-used generic tablet that blocks androgen hormones, and dermatology guidelines support it for adult women with acne, especially breakouts along the jaw and chin that flare with the cycle. A licensed provider reviews your history and blood pressure, and if appropriate prescribes 25 or 50 mg; it is $120 for 30 days, $140 for 60 days or $160 for 90 days.
For hormonal acne in adult women.
| Option | Monthly | Quarterly, 3 months | Start |
|---|---|---|---|
| Spironolactone 25 or 50 mg30 days $120, 60 days $140, 90 days $160 | $120 | $160about $53 a month | Start |
Prices include the online visit, licensed provider review, medication and shipping. Quarterly plans ship three months at a time. Cancel or pause anytime. Available online in Detroit, Metro Detroit and across Michigan, and in other states where our providers are licensed.
Online visits for Detroit, Metro Detroit and Michigan. Questions first? Email support@hoolongevity.com or call (586) 321-3377.
Who it's for
- Adult women with persistent or cyclical acne, often along the jaw and chin
- Women whose acne has not cleared with skincare alone
Not for
- Pregnancy, trying to conceive or breastfeeding
- Kidney disease or high potassium
- Men
Your licensed provider reviews your full history and decides what is appropriate.
How it works
Complete a skin and health questionnaire online
A licensed provider reviews it and decides whether spironolactone is appropriate, and the dose
Your tablets ship in discreet packaging
Give it at least three months; your provider may adjust the dose
What's included
- Online visit and licensed provider review
- Spironolactone tablets (30, 60 or 90 days)
- Shipping in discreet packaging
- Messaging with your care team
Important safety information
- Use reliable birth control: spironolactone should not be taken during pregnancy.
- Common effects include more frequent urination, breast tenderness, irregular periods and dizziness.
- Avoid potassium supplements and salt substitutes unless your provider approves. Your provider may check potassium if you have kidney or heart conditions.
- Get help for muscle weakness, a slow or irregular heartbeat, or fainting.
Prescription only. A licensed provider reviews your health history in an online visit and decides whether this program is appropriate for you. Tell your provider about every medication, supplement, allergy and condition, and whether you are pregnant, trying to conceive or breastfeeding. If you have a severe reaction, trouble breathing, chest pain or swelling of the face or throat, call 911.
Full details: safety information. Updated November 3, 2026.
Questions, answered
Straight answers about Spironolactone for Hormonal Acne.
Does spironolactone work for hormonal acne?
American Academy of Dermatology guidelines support spironolactone for acne in adult women. It usually takes about three months to judge, and results vary.
How much is spironolactone?
Spironolactone is $120 for 30 days, $140 for 60 days or $160 for 90 days, including the visit, provider review and shipping.
Can it help dark spots from acne?
Spironolactone treats the breakouts, which can reduce new marks. Existing dark spots (post-inflammatory hyperpigmentation) fade over time with sunscreen and other skincare your provider may suggest.
Sources
- Reynolds et al., Guidelines of care for the management of acne vulgaris, J Am Acad Dermatol (2024)
- MedlinePlus, Spironolactone
Reviewed November 3, 2026.
Read more
Health GuideReady to start?
A licensed provider reviews your online visit and decides whether Spironolactone for Hormonal Acne is right for you.