Safety, in plain words.

Compounded Semaglutide

• The most common side effects are nausea, vomiting, diarrhea, constipation and stomach pain, especially when the dose goes up. Eat smaller meals and stop eating when full.
• Not for anyone with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN 2). Tell your provider about a lump or swelling in your neck.
• Get help right away for severe stomach pain that does not go away (possible pancreatitis), pain in the upper right belly or yellow skin (possible gallbladder problems), or signs of dehydration.
• If you take insulin or a sulfonylurea, the risk of low blood sugar is higher. Do not use during pregnancy; stop before trying to conceive as your provider advises.
• Measure every dose exactly as labeled. The FDA has received reports of dosing errors with compounded GLP-1 medications, often from confusion about units and syringes.

Not for:

• A personal or family history of medullary thyroid carcinoma or MEN 2
• Pregnancy, trying to conceive or breastfeeding
• A history of pancreatitis, or type 1 diabetes, unless your provider approves
• Anyone under 18

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: Wilding et al., Once-Weekly Semaglutide in Adults with Overweight or Obesity, N Engl J Med (2021), NIDDK, Prescription Medications to Treat Overweight and Obesity, MedlinePlus, Semaglutide Injection, FDA, FDA's concerns with unapproved GLP-1 drugs used for weight loss, FDA, Compounding and the FDA: Questions and Answers. Program page.

Compounded Tirzepatide

• The most common side effects are nausea, vomiting, diarrhea, constipation and stomach pain, especially when the dose goes up. Eat smaller meals and stop eating when full.
• Not for anyone with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN 2). Tell your provider about a lump or swelling in your neck.
• Get help right away for severe stomach pain that does not go away (possible pancreatitis), pain in the upper right belly or yellow skin (possible gallbladder problems), or signs of dehydration.
• If you take insulin or a sulfonylurea, the risk of low blood sugar is higher. Do not use during pregnancy; stop before trying to conceive as your provider advises.
• Measure every dose exactly as labeled. The FDA has received reports of dosing errors with compounded GLP-1 medications, often from confusion about units and syringes.
• Tirzepatide can make birth control pills less effective after you start and after each dose increase. Ask your provider about a backup method.

Not for:

• A personal or family history of medullary thyroid carcinoma or MEN 2
• Pregnancy, trying to conceive or breastfeeding
• A history of pancreatitis, or type 1 diabetes, unless your provider approves
• Anyone under 18

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: Jastreboff et al., Tirzepatide Once Weekly for the Treatment of Obesity, N Engl J Med (2022), NIDDK, Prescription Medications to Treat Overweight and Obesity, MedlinePlus, Tirzepatide Injection, FDA, FDA's concerns with unapproved GLP-1 drugs used for weight loss, FDA, Compounding and the FDA: Questions and Answers. Program page.

Microdose GLP-1

• The most common side effects are nausea, vomiting, diarrhea, constipation and stomach pain, especially when the dose goes up. Eat smaller meals and stop eating when full.
• Not for anyone with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN 2). Tell your provider about a lump or swelling in your neck.
• Get help right away for severe stomach pain that does not go away (possible pancreatitis), pain in the upper right belly or yellow skin (possible gallbladder problems), or signs of dehydration.
• If you take insulin or a sulfonylurea, the risk of low blood sugar is higher. Do not use during pregnancy; stop before trying to conceive as your provider advises.
• Measure every dose exactly as labeled. The FDA has received reports of dosing errors with compounded GLP-1 medications, often from confusion about units and syringes.

Not for:

• A personal or family history of medullary thyroid carcinoma or MEN 2
• Pregnancy, trying to conceive or breastfeeding
• A history of pancreatitis, or type 1 diabetes, unless your provider approves
• Anyone under 18

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: Wilding et al., Once-Weekly Semaglutide in Adults with Overweight or Obesity, N Engl J Med (2021), Jastreboff et al., Tirzepatide Once Weekly for the Treatment of Obesity, N Engl J Med (2022), NIDDK, Prescription Medications to Treat Overweight and Obesity, FDA, FDA's concerns with unapproved GLP-1 drugs used for weight loss, FDA, Compounding and the FDA: Questions and Answers. Program page.

Tirzepatide Sublingual Drops

• The most common side effects are nausea, vomiting, diarrhea, constipation and stomach pain, especially when the dose goes up. Eat smaller meals and stop eating when full.
• Not for anyone with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN 2). Tell your provider about a lump or swelling in your neck.
• Get help right away for severe stomach pain that does not go away (possible pancreatitis), pain in the upper right belly or yellow skin (possible gallbladder problems), or signs of dehydration.
• If you take insulin or a sulfonylurea, the risk of low blood sugar is higher. Do not use during pregnancy; stop before trying to conceive as your provider advises.

Not for:

• A personal or family history of medullary thyroid carcinoma or MEN 2
• Pregnancy, trying to conceive or breastfeeding
• A history of pancreatitis, or type 1 diabetes, unless your provider approves
• Anyone under 18

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: Jastreboff et al., Tirzepatide Once Weekly for the Treatment of Obesity, N Engl J Med (2022), NIDDK, Prescription Medications to Treat Overweight and Obesity, MedlinePlus, Tirzepatide Injection, FDA, Compounding and the FDA: Questions and Answers. Program page.

GLOW Peptide Stack

• Peptides on this site are compounded by licensed US pharmacies on a provider's prescription. They are not FDA-approved and evidence in people is limited. Not for use during pregnancy or breastfeeding. Your licensed provider decides whether any peptide is appropriate for you.
• Injections are given under the skin with a small needle, following the written directions that come with your prescription. Common effects include redness, stinging or a small bump where you inject. Never share or reuse needles, and use a sharps container.
• If you compete in tested sport, this substance may be prohibited. Check the WADA Prohibited List and your sport's rules before starting.

Not for:

• Pregnancy, trying to conceive, or breastfeeding
• Active cancer or a history of cancer unless your provider approves
• Anyone under 18

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: Pickart and Margolina, Regenerative and Protective Actions of the GHK-Cu Peptide, Int J Mol Sci (2018), Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review (2025), FDA, Compounding and the FDA: Questions and Answers, World Anti-Doping Agency, Prohibited List. Program page.

KLOW Peptide Blend

• Peptides on this site are compounded by licensed US pharmacies on a provider's prescription. They are not FDA-approved and evidence in people is limited. Not for use during pregnancy or breastfeeding. Your licensed provider decides whether any peptide is appropriate for you.
• Injections are given under the skin with a small needle, following the written directions that come with your prescription. Common effects include redness, stinging or a small bump where you inject. Never share or reuse needles, and use a sharps container.
• If you compete in tested sport, this substance may be prohibited. Check the WADA Prohibited List and your sport's rules before starting.

Not for:

• Pregnancy, trying to conceive, or breastfeeding
• Active cancer or a history of cancer unless your provider approves
• Anyone under 18

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: Pickart and Margolina, Regenerative and Protective Actions of the GHK-Cu Peptide, Int J Mol Sci (2018), Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review (2025), Kannengiesser et al., Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease (2008), FDA, Compounding and the FDA: Questions and Answers, World Anti-Doping Agency, Prohibited List. Program page.

GHK-Cu Injection

• Peptides on this site are compounded by licensed US pharmacies on a provider's prescription. They are not FDA-approved and evidence in people is limited. Not for use during pregnancy or breastfeeding. Your licensed provider decides whether any peptide is appropriate for you.
• Injections are given under the skin with a small needle, following the written directions that come with your prescription. Common effects include redness, stinging or a small bump where you inject. Never share or reuse needles, and use a sharps container.

Not for:

• Pregnancy, trying to conceive, or breastfeeding
• Active cancer or a history of cancer unless your provider approves
• Anyone under 18

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: Pickart and Margolina, Regenerative and Protective Actions of the GHK-Cu Peptide, Int J Mol Sci (2018), FDA, Compounding and the FDA: Questions and Answers. Program page.

MOTS-c

• Peptides on this site are compounded by licensed US pharmacies on a provider's prescription. They are not FDA-approved and evidence in people is limited. Not for use during pregnancy or breastfeeding. Your licensed provider decides whether any peptide is appropriate for you.
• Injections are given under the skin with a small needle, following the written directions that come with your prescription. Common effects include redness, stinging or a small bump where you inject. Never share or reuse needles, and use a sharps container.
• If you compete in tested sport, this substance may be prohibited. Check the WADA Prohibited List and your sport's rules before starting.

Not for:

• Pregnancy, trying to conceive, or breastfeeding
• Active cancer or a history of cancer unless your provider approves
• Anyone under 18

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: MOTS-c, the Most Recent Mitochondrial Derived Peptide in Human Aging and Age-Related Diseases (2022), Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging (2023), FDA, Compounding and the FDA: Questions and Answers, World Anti-Doping Agency, Prohibited List. Program page.

BPC-157 Injection

• Peptides on this site are compounded by licensed US pharmacies on a provider's prescription. They are not FDA-approved and evidence in people is limited. Not for use during pregnancy or breastfeeding. Your licensed provider decides whether any peptide is appropriate for you.
• Injections are given under the skin with a small needle, following the written directions that come with your prescription. Common effects include redness, stinging or a small bump where you inject. Never share or reuse needles, and use a sharps container.
• If you compete in tested sport, this substance may be prohibited. Check the WADA Prohibited List and your sport's rules before starting.

Not for:

• Pregnancy, trying to conceive, or breastfeeding
• Active cancer or a history of cancer unless your provider approves
• Anyone under 18

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review (2025), FDA, Compounding and the FDA: Questions and Answers, World Anti-Doping Agency, Prohibited List. Program page.

BPC-157 + TB-500 Injection

• Peptides on this site are compounded by licensed US pharmacies on a provider's prescription. They are not FDA-approved and evidence in people is limited. Not for use during pregnancy or breastfeeding. Your licensed provider decides whether any peptide is appropriate for you.
• Injections are given under the skin with a small needle, following the written directions that come with your prescription. Common effects include redness, stinging or a small bump where you inject. Never share or reuse needles, and use a sharps container.
• If you compete in tested sport, this substance may be prohibited. Check the WADA Prohibited List and your sport's rules before starting.

Not for:

• Pregnancy, trying to conceive, or breastfeeding
• Active cancer or a history of cancer unless your provider approves
• Anyone under 18

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review (2025), FDA, Compounding and the FDA: Questions and Answers, World Anti-Doping Agency, Prohibited List. Program page.

PT-141 for Women

• Nausea is the most common side effect: in the approved product's trials about 40% of women had nausea, compared with about 1% on placebo.
• It can cause a temporary rise in blood pressure and a drop in heart rate after each dose.
• Darkening of the gums and skin on the face or breasts has been reported, and may not fully fade.
• Tell your provider about every medication, especially oral naltrexone.

Not for:

• Uncontrolled high blood pressure or known heart disease
• Pregnancy
• Use after menopause is off-label, with less evidence, and is not what this page promotes

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: FDA, Drug Trials Snapshots: Vyleesi (bremelanotide), FDA, Compounding and the FDA: Questions and Answers. Program page.

PT-141 for Men

• Nausea, flushing and headache are the most common side effects.
• It can cause a temporary rise in blood pressure and a drop in heart rate after each dose.
• Darkening of the gums and skin has been reported.
• Tell your provider about every medication, especially oral naltrexone.

Not for:

• Uncontrolled high blood pressure or known heart disease
• Anyone under 18

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: FDA, Drug Trials Snapshots: Vyleesi (bremelanotide), FDA, Compounding and the FDA: Questions and Answers. Program page.

ED Treatment for Men

• Never take with nitrates or riociguat: the combination can cause a dangerous drop in blood pressure.
• Common effects include headache, flushing, stuffy nose, indigestion and back pain (tadalafil).
• Get emergency help for an erection that lasts more than 4 hours, sudden vision or hearing loss, or chest pain during sex.
• Alcohol and some blood pressure medicines can increase dizziness.

Not for:

• Anyone who takes nitrates (such as nitroglycerin) or riociguat
• Men told to avoid sexual activity because of heart disease
• Recent heart attack or stroke, unless your provider approves

Sources: MedlinePlus, Sildenafil, MedlinePlus, Tadalafil. Program page.

Menopause Hormone Therapy

• Common early effects include breast tenderness, bloating, headaches, mood changes and spotting, which often settle in the first months.
• Estrogen can raise the risk of blood clots and stroke, especially as pills and when started later in life. Your provider weighs your age, timing and history.
• If you have a uterus, estrogen without a progestogen raises the risk of endometrial cancer; this boxed warning remains on systemic estrogen-alone products.
• Report any bleeding after menopause, chest pain, sudden leg swelling or stroke symptoms right away.
• Biest lotions are compounded. Compounded hormones are not FDA-approved, and The Menopause Society and ACOG prefer FDA-approved hormone therapy when a suitable product exists.

Not for:

• A history of breast or uterine cancer, blood clots, stroke or heart attack
• Active liver disease or unexplained vaginal bleeding
• Pregnancy

Sources: The 2022 hormone therapy position statement of The North American Menopause Society, Menopause (2022), FDA, FDA approves labeling changes to menopausal hormone therapy products (Feb 12, 2026), HHS fact sheet, FDA initiates removal of boxed warnings from menopausal hormone therapy products (Nov 10, 2025), National Cancer Institute, Menopausal Hormone Therapy and Cancer, ACOG Clinical Consensus No. 6, Compounded Bioidentical Menopausal Hormone Therapy (2023), Avis et al., Duration of Menopausal Vasomotor Symptoms Over the Menopause Transition (SWAN), JAMA Intern Med (2015). Program page.

Perimenopause Care

• Standard hormone therapy doses are not birth control, so some women in perimenopause still need contraception.
• Other conditions, such as thyroid problems, can cause similar symptoms, so your provider may suggest checking for them.
• If you have significant anxiety, panic or low mood, tell your provider. If you ever have thoughts of harming yourself, call or text 988.

Not for:

• Emergencies: call 911 for chest pain or stroke symptoms
• Anyone who needs an in-person exam first, which your provider will advise

Sources: National Institute on Aging, What Is Menopause?, The 2022 hormone therapy position statement of The North American Menopause Society, Menopause (2022), Avis et al., Duration of Menopausal Vasomotor Symptoms Over the Menopause Transition (SWAN), JAMA Intern Med (2015), UBC Centre for Menstrual Cycle and Ovulation Research, Can a blood test tell me whether I am in menopause?, The 2023 nonhormone therapy position statement of The North American Menopause Society. Program page.

Hair Regrowth Spray

• Some shedding in the first weeks is common with minoxidil and usually settles.
• Scalp dryness, itching or irritation can occur; tell your care team if it is bothersome.
• Unwanted facial hair growth can happen if the spray runs onto the face. Wash your hands after use.
• Get help for chest pain, a fast heartbeat, fainting or sudden swelling of the hands or feet.

Not for:

• Pregnancy or breastfeeding
• Sudden patchy loss, a painful or scaly scalp, or bald patches with scarring, which need an in-person dermatology exam
• Allergy to minoxidil, tretinoin or fluocinolone

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: American Academy of Dermatology, Hair loss in people with darker skin, MedlinePlus, Minoxidil Topical, FDA, Compounding and the FDA: Questions and Answers. Program page.

GHK-Cu Copper Peptide Cream

• Stop using it and contact your care team if you develop redness, stinging, itching, swelling or a rash.
• Patch test on a small area first if your skin is reactive.
• For external use only. Avoid eyes and mucous membranes.

Not for:

• Anyone with a known copper allergy or allergy to an ingredient
• Broken, infected or freshly treated skin unless your provider says otherwise
• Pregnancy or breastfeeding, where there is not enough data

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: Pickart and Margolina, Regenerative and Protective Actions of the GHK-Cu Peptide, Int J Mol Sci (2018), FDA, Compounding and the FDA: Questions and Answers. Program page.

Spironolactone for Hormonal Acne

• Use reliable birth control: spironolactone should not be taken during pregnancy.
• Common effects include more frequent urination, breast tenderness, irregular periods and dizziness.
• Avoid potassium supplements and salt substitutes unless your provider approves. Your provider may check potassium if you have kidney or heart conditions.
• Get help for muscle weakness, a slow or irregular heartbeat, or fainting.

Not for:

• Pregnancy, trying to conceive or breastfeeding
• Kidney disease or high potassium
• Men

Sources: Reynolds et al., Guidelines of care for the management of acne vulgaris, J Am Acad Dermatol (2024), MedlinePlus, Spironolactone. Program page.

NAD+

• Commonly reported effects include flushing, nausea, headache, injection-site stinging and a feeling of chest tightness, especially at higher doses.
• The FDA has received reports of chills, shaking and vomiting after NAD+ injections made with unsuitable ingredients, which is why Golden Glow prescriptions are filled only by licensed US pharmacies.

Not for:

• Pregnancy or breastfeeding
• Anyone who has reacted badly to NAD+ before

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: Radenkovic and Verdin, Clinical Evidence for Targeting NAD Therapeutically, Pharmaceuticals (2020), FDA, FDA reminds compounders to use ingredients suitable for sterile compounding, FDA, Compounding and the FDA: Questions and Answers. Program page.

Sermorelin

• Injections are given under the skin with a small needle, following the written directions that come with your prescription. Common effects include redness, stinging or a small bump where you inject. Never share or reuse needles, and use a sharps container.
• Flushing, headache, dizziness and trouble sleeping have been reported.
• If you compete in tested sport, this substance may be prohibited. Check the WADA Prohibited List and your sport's rules before starting.

Not for:

• Pregnancy or breastfeeding
• Active cancer or a history of cancer unless your provider approves
• Untreated thyroid problems
• Anyone under 18

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: Walker, Sermorelin: a better approach to management of adult-onset growth hormone insufficiency? Clin Interv Aging (2006), FDA, Compounding and the FDA: Questions and Answers, World Anti-Doping Agency, Prohibited List. Program page.

Glutathione Injection

• Injections are given under the skin with a small needle, following the written directions that come with your prescription. Common effects include redness, stinging or a small bump where you inject. Never share or reuse needles, and use a sharps container.
• Stop and get help for wheezing, trouble breathing, a rash or swelling of the face.

Not for:

• Pregnancy or breastfeeding
• Asthma that flares with sulfur-containing medicines, unless your provider approves
• Skin lightening, which Golden Glow does not offer

Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.

Sources: Richie et al., Randomized controlled trial of oral glutathione supplementation on body glutathione stores, Eur J Nutr (2015), FDA, Compounding and the FDA: Questions and Answers. Program page.