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No. 04 · Weight loss
Tirzepatide Sublingual Drops
Daily drops under the tongue, no needles
Tirzepatide sublingual drops are a compounded, needle-free form of tirzepatide that you place under your tongue each day. There are no published large human trials of tirzepatide taken this way, so how much is absorbed and how well it works are not established; a licensed provider decides whether it is appropriate.
A needle-free tirzepatide option.
| Option | Monthly | Start |
|---|---|---|
| Tirzepatide drops, 15 mLStarting size | $225 | Start |
| Tirzepatide drops, 30 mLMaintenance size | $300 | Start |
Prices include the online visit, licensed provider review, medication and shipping. Quarterly plans ship three months at a time. Cancel or pause anytime. Available online in Detroit, Metro Detroit and across Michigan, and in other states where our providers are licensed.
Online visits for Detroit, Metro Detroit and Michigan. Questions first? Email support@hoolongevity.com or call (586) 321-3377.
Who it's for
- Adults who qualify for a GLP-1 and strongly prefer no needles
- Women who understand that evidence for the sublingual form is limited
Not for
- A personal or family history of medullary thyroid carcinoma or MEN 2
- Pregnancy, trying to conceive or breastfeeding
- A history of pancreatitis, or type 1 diabetes, unless your provider approves
- Anyone under 18
Your licensed provider reviews your full history and decides what is appropriate.
How it works
Complete the online weight visit
A licensed provider reviews it and decides whether the drops are appropriate
Your drops ship from a licensed US pharmacy
Use as labeled each day and message your care team with questions
What's included
- Online visit and licensed provider review
- Compounded tirzepatide sublingual drops, 15 mL or 30 mL
- Shipping
- Messaging with your care team
Important safety information
- The most common side effects are nausea, vomiting, diarrhea, constipation and stomach pain, especially when the dose goes up. Eat smaller meals and stop eating when full.
- Not for anyone with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN 2). Tell your provider about a lump or swelling in your neck.
- Get help right away for severe stomach pain that does not go away (possible pancreatitis), pain in the upper right belly or yellow skin (possible gallbladder problems), or signs of dehydration.
- If you take insulin or a sulfonylurea, the risk of low blood sugar is higher. Do not use during pregnancy; stop before trying to conceive as your provider advises.
- Compounded medications are prepared by a licensed US pharmacy for an individual patient. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality before they are dispensed.
Prescription only. A licensed provider reviews your health history in an online visit and decides whether this program is appropriate for you. Tell your provider about every medication, supplement, allergy and condition, and whether you are pregnant, trying to conceive or breastfeeding. If you have a severe reaction, trouble breathing, chest pain or swelling of the face or throat, call 911.
Full details: safety information. Updated November 3, 2026.
Questions, answered
Straight answers about Tirzepatide Sublingual Drops.
Do tirzepatide drops work as well as injections?
That is not known. There are no published large human trials of tirzepatide taken under the tongue, so absorption and results are not established. The weekly injection is the form studied in large trials.
How much are the drops?
Tirzepatide sublingual drops are $225 a month for the 15 mL starting size and $300 a month for the 30 mL size, including the visit, provider review and shipping.
Read more
Health GuideReady to start?
A licensed provider reviews your online visit and decides whether Tirzepatide Sublingual Drops is right for you.